Please inform your doctor if you have glaucoma or increased pressure in the eye, a stomach ulcer, an enlarged prostate, bladder problems or difficulty urinating, an overactive thyroid (hyperthyroidism), hypertension or any type of heart problems or asthma.

Do not take chlorpheniramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan®), phenelzine (Nardil®), or tranylcypromine (Parnate®) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects. You may not be able to take this medicine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Moreover, talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These products may contain medicines similar to chlorpheniramine, which could lead to an overdose of antihistamine.

Additionally, tell your doctor if you are taking any of the following medicines: anxiety or sleep medicines such as alprazolam (Xanax®), diazepam (Valium®), chlordiazepoxide (Librium®), temazepam (Restoril®), or triazolam (Halcion®); medications for depression such as amitriptyline (Elavil®), doxepin (Sinequan®), nortriptyline (Pamelor®), fluoxetine (Prozac®), sertraline (Zoloft®), or paroxetine (Paxil®); or any other medications that make you feel drowsy, sleepy, or relaxed.

Chlorpheniramine is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take this medicine without first talking to your doctor if you are pregnant. So too, this medication passes into breast milk. Infants are especially sensitive to the effects of antihistamines, and serious side effects could occur in a nursing baby.

If you are over 60 years of age, you may be more likely to experience side effects from chlorpheniramine. You may require a lower dose of this medication.

Use cautiously when driving, operating machinery, or performing other hazardous activities. This medicine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Alcohol may also increase drowsiness and dizziness while you are taking chlorpheniramine.

 

FDA Information

Why is this medication prescribed?

Other uses for this medicine

Dosage and using this medicine

What should I do if I forget a dose?

What side effects can this medication cause?

What storage conditions are needed for this medicine?

In case of an emergency/overdose